Description Amprolium is a coccidiostat (antiprotozoal) used for the treatment and prevention of coccidiosis in calves, sheep, goats, chickens (broilers and breeders) and other fowl such as turkeys, with activity against Eimeria spp., especially Eimeria tenella and Eimeria necatrix. It is a thiamine (vitamin B1) analogue and its pharmacological effect relies on competitive inhibition of thiamine uptake. Amprolium competitively inhibits the active transport of thiamine in isolated second-generation schizonts of Eimeria spp. and in host intestinal cells. Upon ingestion of amprolium, the coccidia experience thiamine deficiency and starve from malnutrition Contra indications The use of amprolium is prohibited from a laying age onwards. Do not administer to poultry whose eggs are intended for human consumption. Do not administer to animals with impaired hepatic and/or renal functions. Do not administer to turkeys before the age of 8 to 10 weeks. Side effects Overdosage of amprolium can suppress weight gain in broilers and cause polyneuritis. Long-term administration of amprolium in high doses may result in thiamine (vitamin B1) deficiency in the host. To treat amprolium overdose, thiamine should be administered parenterally or orally. Withdrawal times - For meat: Calves, goats, sheep : 3 days. Poultry : 3 days. Packaging Sachet of 100 g and jar of 1000 g.

Description Amprolium is a coccidiostat (antiprotozoal) used for the treatment and prevention of coccidiosis in calves, sheep, goats, chickens (broilers and breeders) and other fowl such as turkeys, with activity against Eimeria spp., especially Eimeria tenella and Eimeria necatrix. It is a thiamine (vitamin B1) analogue and its pharmacological effect relies on competitive inhibition of thiamine uptake. Amprolium competitively inhibits the active transport of thiamine in isolated second-generation schizonts of Eimeria spp. and in host intestinal cells. Upon ingestion of amprolium, the coccidia experience thiamine deficiency and starve from malnutrition Contra indications The use of amprolium is prohibited from a laying age onwards. Do not administer to poultry whose eggs are intended for human consumption. Do not administer to animals with impaired hepatic and/or renal functions. Do not administer to turkeys before the age of 8 to 10 weeks. Side effects Overdosage of amprolium can suppress weight gain in broilers and cause polyneuritis. Long-term administration of amprolium in high doses may result in thiamine (vitamin B1) deficiency in the host. To treat amprolium overdose, thiamine should be administered parenterally or orally. Withdrawal times - For meat: Calves, goats, sheep : 3 days. Poultry : 3 days. Packaging Sachet of 100 g and jar of 1000 g.